Bioactivity | 5,7-Dichloropyrazolo[1,5-a]pyrimidine (fragment 5) is a pyrazolopyrimidine phosphodiesterase 10A(PDE10A) inhibitor (Ki=24 μM). 5,7-Dichloropyrazolo[1,5-a]pyrimidine can be used in the study of schizophrenia[1]. | ||||||
CAS | 57489-77-7 | ||||||
Formula | C6H3Cl2N3 | ||||||
Molar Mass | 188.01 | ||||||
Appearance | 固体 | ||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||
Storage | Store at room temperature 3 years
|
||||||
Reference | [1]. Raheem IT, et al. Discovery of pyrazolopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia. Bioorg Med Chem Lett. 2016 Jan 1;26(1):126-32. |