PeptideDB

5,7-Dichloropyrazolo[1,5-a]pyrimidine

CAS: 57489-77-7 F: C6H3Cl2N3 W: 188.01

5,7-Dichloropyrazolopyrimidine (fragment 5) is a pyrazolopyrimidine phosphodiesterase 10A(PDE10A) inhibitor (Ki=24 μM).
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Bioactivity 5,7-Dichloropyrazolo[1,5-a]pyrimidine (fragment 5) is a pyrazolopyrimidine phosphodiesterase 10A(PDE10A) inhibitor (Ki=24 μM). 5,7-Dichloropyrazolo[1,5-a]pyrimidine can be used in the study of schizophrenia[1].
CAS 57489-77-7
Formula C6H3Cl2N3
Molar Mass 188.01
Appearance 固体
Transport Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Reference [1]. Raheem IT, et al. Discovery of pyrazolopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia. Bioorg Med Chem Lett. 2016 Jan 1;26(1):126-32.